Measurement of extracellular vesicles and their role in cancer-associated thrombosis
Extracellular vesicles (EV) are submicron vesicles released from activated cells, apoptotic cells and cancer cells...
Basic Mechanisms
Cancers as coagulant mosaics
Cancers are potent inducers of abnormal blood clotting, which usually heralds a more aggressive course of the disease...
Arterial Thromboembolism in Occult Cancer
In 1865, Armand Trousseau famously described unexplained thrombotic events as a first manifestation of occult...
Mouse models of cancer-associated thrombosis
Cancer patients have 4-7 fold increased risk of venous thromboembolism (VTE) compared with a general population ....
Disseminated Intravascular coagulation in solid and hematological cancers
Introduction There is a clear relationship between malignancy and deranged coagulation. Patients with cancer are at...
Cancer’s Achilles heel exposed
Centriole amplification and centriole size deregulation are a recurrent feature of cancer cells, a screening of the...
The role of polymorphisms in coagulation factor genes in cancer susceptibility
Mari Tinholt1,2, Nina Iversen1 and Per Morten Sandset2,3,* 1Department of Medical Genetics, Oslo University Hospital,...
The role of microparticles in VTE
Cancer-associated venous thromboembolism (VTE) causes significant morbidity and mortality in patients and constitutes...
Cancer-related thrombosis in women
There is ample evidence confirming that cancer predisposes to thrombosis, while products of activation of the...