Yohei Hisada

Yohei Hisada earned his Ph.D. in the University of Tokyo in 2014. During his graduate studies, he developed a new method for cancer therapy/diagnosis by targeting fibrin in cancer tissue using a monoclonal antibody produced in Dr. Yasuhiro Matsumura’s laboratory. In 2014, he joined Dr. Nigel Mackman’s laboratory in the University of North Carolina at Chapel Hill. Currently, as a postdoctoral fellow, he is studying the mechanisms of cancer-associated venous thrombosis using mouse models.


Mouse models of cancer-associated thrombosis
Basic Mechanism

Mouse models of cancer-associated thrombosis

The incidence of VTE is varied with cancer type, suggesting that there may be cancer-type specific mechanisms. However, the underlying mechanisms have not been elucidated. Mouse models are used to investigate the mechanisms of cancer-associated thrombosis. Many different mouse models have been established that vary by mouse strains, cancer cells, tumor sites and thrombosis models.

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