The Pediatric Issue

 

This special issue of ICTHIC magazine will focus upon challenging issues dealing with children with cancer and thrombosis, the potential role of thrombophilic risk factors and current and future treatments.

 

Developmental hemostasis and its relevance to pediatric thrombosis

by Gili Kenet

While knowledge of arterial thromboembolism prevalence and risk factors among adult cancer patients is currently growing, there seems to be only scarce information regarding arterial thrombosis in general or stroke in particular, among patients and survivors of pediatric cancer.

by Gili Kenet

While knowledge of arterial thromboembolism prevalence and risk factors among adult cancer patients is currently growing, there seems to be only scarce information regarding arterial thrombosis in general or stroke in particular, among patients and survivors of pediatric cancer.

by CH van Hommen

The enlarged intensity of the primary treatment for cancer results in more frequent severe side effects, including myelosuppression, infection, and venous thromboembolism. VTE has become increasingly diagnosed in children in general and the incidence of VTE appeared to have augmented over time in children with cancer, as well.

by Ulrike Nowak-Göttl & Gili Kenet

Venous thromboembolism in children is a rare disease usually as a secondary complication of primary underlying diseases such as congenital heart disease, sepsis, cancer, or after therapeutic interventions such as central venous lines. In children with cancer the rates of VTE vary on cancer type based on the diagnostic imaging modality and whether VTE was rated as symptomatic or asymptomatic.

by Leonardo Brandao

This review will briefly summarize the knowledge accumulated on the topic of DOACs in children to date, detailing the ongoing pediatric trials and speculating on the appropriateness of their use.

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